4,6-dichloro-1H-Indole-2-carboxylic acid ethyl ester

4,6-dichloro-1H-Indole-2-carboxylic acid ethyl ester - Names and Identifiers

Name	Ethyl 4,6-dichloroindole-2-carboxylate
Synonyms	ETHYL,4,6-DICLOROINDOLE-2-CARBOXYLATE Ethyl 4,6-dichloroindole-2-carboxylate ETHYL 4,6-DICHLOROINDOLE-2-CARBOXYLATE Ethyl 4,6-dichloro-1H-indole-2-carboxylate ETHYL 4,6-DICHLORO-1H-INDOLE-2-CARBOXYLATE ethyl pyruvate-3,5-di-chlorophenylhydrazone 4,6-DICHLOROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 4,6-dichloro-1H-Indole-2-carboxylic acid ethyl ester 4,6-DICHLORO-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER 1H-Indole-2-carboxylic acid, 4,6-dichloro-, ethyl ester
CAS	53995-82-7
InChI	InChI=1/C11H9Cl2NO2/c1-2-16-11(15)10-5-7-8(13)3-6(12)4-9(7)14-10/h3-5,14H,2H2,1H3

4,6-dichloro-1H-Indole-2-carboxylic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C11H9Cl2NO2
Molar Mass	258.1
Density	1.432±0.06 g/cm3(Predicted)
Melting Point	171-172
Boling Point	405.0±40.0 °C(Predicted)
Flash Point	198.7°C
Vapor Presure	9.06E-07mmHg at 25°C
pKa	13.21±0.30(Predicted)
Storage Condition	2-8℃
Refractive Index	1.637

4,6-dichloro-1H-Indole-2-carboxylic acid ethyl ester - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

4,6-dichloro-1H-Indole-2-carboxylic acid ethyl ester - Introduction

Ethyl 4, is an organic compound with the chemical formula C12H8Cl2NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Ethyl 4, white to light yellow crystal or crystalline powder.
-Solubility: It is soluble in organic solvents such as ethanol, chloroform and dichloromethane, but insoluble in water.

Use:
- Ethyl 4, is often used as an intermediate in organic synthesis for the synthesis of indole derivatives and other organic compounds.
-It also has certain applications in the pharmaceutical field, and can be used to study the synthesis of new drugs or as an intermediate for certain drugs.

Preparation Method:
Ethyl 4, the synthesis method of pyridine is generally obtained by the reaction of 4,6-dichloro indole and ethyl formate. The commonly used synthesis methods include:
-Reaction 4,6-dichloroindole and ethyl formate under appropriate reaction conditions to obtain the target product.
-The use of catalysts such as alkyd catalysts can improve the selectivity and yield of the reaction.

Safety Information:
- Ethyl 4, has low toxicity under general use conditions.
-As a chemical, care should be taken to prevent its contact with skin, eyes and mouth, and relevant safety practices should be observed, such as wearing appropriate protective equipment (e. g. gloves, goggles).
-When storing, it should be placed in a cool, dry, well-ventilated place, and avoid contact with oxidants, acids and alkalis.

Please note that when using chemicals, you should strictly abide by safe operating regulations, and seek professional guidance when needed.

Last Update：2024-04-09 15:17:58